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Odisha Review ; : 30-31, 2021.
Article in English | CAB Abstracts | ID: covidwho-1837660

ABSTRACT

The molecular structure of 2-Deoxy D-Glucose is exactly like D-Glucose except for the fact that the former has no hydroxyl group on the carbon atom at the position 2 but instead has a hydrogen atom. Glucose can be of two types: one which turns the plane of the polarized light, when passed through its solution in water, towards right is called Dextrorotatory or D-Glucose and the other which turns it towards left is called Levorotatory or LGlucose. Chemists call glucose as an aldohexose, indicating that it is made up of six carbon atoms, one of which is an aldehyde group and the rest contain hydrogen atoms and hydroxyl groups. In other words, it has one oxygen atom less than D-Glucose and therefore, is called 2-Deoxy-D-Glucose. The Drugs Controller General of India granted approval (May 17 2021) for use of 2 DG drug after it went through too extensive successful clinical trials. Now, the drug has been recommended to be used in moderate cases which have to be taken orally mixed with water, 2 times a day for 5 to 7 days. It showed that the drug was able to reduce oxygen dependency by the third day and reduce the hospital stay considerably.

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